EWG Risk Score:
What is it:
Glucose Oxidase is actually an enzyme that's naturally present in honey and even on the surface of some fungi. Glucose oxidase works as a preservative by releasing hydrogen peroxide, which is toxic to bacteria. (Source) It is typically used with lactose peroxidase for full preservative effect in a cosmetic formulation.
- According to MSDS sheets, it is an eye irritant, a skin irritant a lung irritant and "prolonged or repeated exposure may lead to irreversible damage to health." (Source) However, this may not be an accurate risk asessment, as this information applies to the pure powder. Concentrations of glucose oxidase in a cosmetic formula would be much lower, and thus the risks would be as well.
- Toxilogical data for Glucose Oxidase is highly lacking. Here is a screen shot of one MSDS sheet:
As you can see, "no data available" seems to be a theme with this ingredient.
I view this ingredient somewhat with caution because of its lack of safety data, and wouldn't recommend it for someone with extremely sensitive skin. I also find it somewhat concerning because it creates hydrogen peroxide, which creates free radicals on the skin. (Source) However, this would be in very small amounts, and the effects may be negated by other ingredients. But it is still a concerning effect.